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KMID : 0613820070170081147
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Journal of Life Science
2007 Volume.17 No. 8 p.1147 ~ p.1151
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The Evaluation of Anti-wrinkle Effects in Oriental Herb Extract
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Kang Kum-Suk
Kim In-Deok
Kwon Ryun-Hee
Heo Ye-Young
Oh Sang-Hoon
Kim Min-Ah
Jung Hye-Jin
Kang Hwan-Yul
Ha Bae-Jin
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Abstract
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The human skin is constantly exposed to environmental irritants such as ultraviolet, smoke and chemicals. Free radicals and reactive oxygen species caused by them play critical roles in cellular damage. They not only injure the skin structure but also participate in the immensely complex inflammatory reaction. Anti-wrinkle effects of the Oriental herb extracts (OHE) were evaluated by the determination of anti-oxidation, collagenase inhibition and collagen synthesis in normal human fibroblast. OHE showed antioxidative activity as high as vitamin C, trolox and DL-penicillamine. Also OHE showed promotive effect on collagen synthesis and inhibitory effect on collagenase activity. These results demonstrated that OHE could be useful as an anti-wrinkle cosmetic ingredient.
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KEYWORD
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Oriental Herb, anti-wrinkle, anti-oxidation, collagen synthesis
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